Collection
- Salvador Araneta papers, 1921-19721
- Samuel Dickie scrapbook, 1868-18791
- Samuel Miller Brownell and Esther Delzell Brownell papers, 1900-20031
- School for Environment and Sustainability (University of Michigan) records, 1903 - 20121
- Schuler's Restaurant Records, 1944-20021
- Sebastian Spering Kresge papers, 1937-19661
- Shirley Wheeler Smith Papers, 1881-19591
- Shirley Wohlfield Papers, 1972-19881
- Skulda V. Banér papers, 1900-1975 (majority within 1920-1964)1
- Sligh Family Papers, 1842-20121
- Smith-Parker-Hicks-Winegar Family Papers, 1821-2012 (majority within 1880-1952)1
- Southwestern Michigan Urban League records, 1962-20071
- St. Matthew's and St. Joseph's Episcopal Church (Detroit, Mich.) Records, 1884-20061
- Standish Backus papers, 1919-19421
- Stanley G. Fontanna scrapbook, 1913-19191
- Stanley M. Matthews scrapbook, 1895-1899, 19031
- Stanley P. Smith scrapbook, 1913-19171
- Starr Commonwealth records, 1916-2015 (majority within 1950-2000)1
- Stearns Collection of Musical Instruments records, 1897-1921, 1977-20061
- Stowell Cortland Stebbins scrapbooks, 1909-19111