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Birmingham, Michigan, businesswoman, Democratic Regent of the University of Michigan; contain materials relating to her life and interest in the Philippines, especially during the administration of Frank Murphy, during World War II, and during the presidency of Ferdinand Marcos; papers relating to her interest in University of Michigan history; and photographs.

The Irene Murphy collections has been arranged into the following series: Correspondence; Murphy family; University of Michigan Board of Regents; Philippines interests and activities; Other topics; Scrapbooks and clippings; Sound recording; and Photographs.