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Sandra S. Cole is a sexologist and professor (retired) at the University of Michigan School of Medicine. This collection documents Cole’s transgender advocacy, including the University of Michigan’s Comprehensive Gender Services Program, the inclusion of gender identity in the non-discrimination policies of the University of Michigan and the City of Ann Arbor, and her presentations, public appearances, and consultation work on transgender issues in the late 1990s and early 2000s.

The Sandra S. Cole papers document Cole's work on behalf of the transgender community at the University of Michigan and in Ann Arbor. A number of the papers in the collection are photocopies of items held by the Kinsey Institute for Research in Sex, Gender, and Reproduction at Indiana University. The collection consists of four series: Comprehensive Gender Services Program, University of Michigan Non-Discrimination Policy, Lectures, Public Appearances, and Consultation Work, and Transgender Reference Materials.