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A unit of the University of Michigan's Institute of Science and Technology which conducts and sponsors interdisciplinary studies of fresh water lake ecology. It is the successor to the Great Lakes Research Institute and the Great Lakes Research Division of the University of Michigan. Primarily research data, analysis, and reports on two major studies: the Coherent Area Study of Lake Michigan, 1963-1971, and the Donald C. Cook Nuclear Power Plant Studies, 1967-1983.

The records in this collection are largely research files from the period when John C. Ayers was director of research for the Great Lakes Research Division. The bulk of the records document two large research projects: the Coherent Area Study, 1963-1971, and Donald C. Cook Nuclear Power Plant Studies, 1967-1983. There is also documentation of several smaller research projects. The research files include reports, field and laboratory data, and a variety of logs documenting data collection. The collection has few if any administrative records of the GLRD or its successors.

The records are arranged in ten series: Historical Information, Coherent Area Study, Ship's Logs, Donald C. Cook Power Plant Studies, Lake Michigan Ice Studies, John C. Ayers Research Files, Administration, Grants, Topical files, and Visual materials. Because the records contain a variety of formats, including slides, fan-fold computer printouts, and outsize volumes, some subgroups and series are split between ranges of box numbers. The summary contents list provides an overview of the physical arrangement of the records.

Department of Biology (established 1986) of the University of Michigan, and of its predecessor unit, the Division of Biological Sciences, and the departments (Botany and Zoology) that comprised the division. In 2001, the unit name was changed to Department of Molecular, Cellular, and Developmental Biology. Records include minutes, correspondence, course materials, and various subject files.

The Department of Molecular, Cellular, and Developmental Biology, 1879-1992, measure 5 linear feet and include minutes, correspondence, course materials, and various subject files. The records are organized into ten series: Departmental and Divisional Records, Printed Material, Divisional Administration, Staff, Academics, Students, Logistics, Biological Units, Outside Relations, and Promotions.

The records of the Division of Research Development and Administration (1919-1996) encompass the DRDA and all of its predecessor organizations, including the Department of Engineering Research, the Engineering Research Institute, the University of Michigan Research Institute, and the Office of Research Administration. Record types include correspondence, topical subject files, research grant files, meeting minutes, financial records, and photographs.

The records of the Division of Research Development and Administration (1919-1996) encompass both the DRDA and all of its predecessor organizations. The papers have been divided into seven major series: Governing and Oversight Bodies (1919-1964), Staff and Committee Records (ca. 1922-1979), Administrative Files (1922-1972), Correspondence Files (1943-1972), Willow Run Laboratories (1946-1966), Directors' Files, and several boxes of Research Grant Files on microfilm. There are also four smaller series: the Engineering College Research Council (1959-1961), Review of the DRDA - Report to Harold Shapiro, 1980, Engineering Research Institute - miscellaneous research reports, Photographs, and Programmed Research Information System at Michigan (PRISM) Reports.