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Collection

Human Gene Therapy Initiative records, 1988-1992

3 linear feet

Molecular Medicine and Genetics Division established within the Department of Internal Medicine in 1991 to coordinate aspects of University of Michigan research as part of the Human Genome Project, an international effort to identify and map the genetic structure of the human chromosomes. Planning records from the University of Michigan Internal Medicine Molecular Medicine and Genetics Division relating to the unit's participation in human gene therapy; include minutes, development and feasibility studies, and a copy of the program proposal, "Experimental Models of Gene Therapy."

The records of the University of Michigan Department of Internal Medicine Molecular Medicine and Genetics Division, dating from 1988 to 1992, document some of the earliest gene therapy endeavors, centering on successful efforts to establish a Human Genome Center at the university. The bulk of the records focus on the development of the program project grant, "Experimental Models of Gene Therapy." The collection, organized in four series, includes Human Gene Therapy Initiative (an early effort to establish a Human Genome Center at the University of Michigan), Scientific Basis for Gene Therapy, Experimental Models of Gene Therapy, and Center for Excellence in Gene Therapy files. The organization of the series reflects the general chronology of the development of gene therapy research at the University of Michigan

Collection

Ivan F. Duff papers, 1947-1994 (majority within 1976-1982)

4.5 linear feet

Rheumatologist and founder of the University of Michigan Turner Geriatric Clinic; director of the Rackham Arthritis Research Unit and chief of the Arthritis Division. Records relating to the development of gerontological medicine at the University of Michigan and the founding of the Turner Geriatric Clinic; includes biographical material, correspondence, planning records, name files, and topical files relating to gerontology and rheumatic diseases.

The Ivan Duff papers consist of four and one-half linear feet of records dating from 1947 to 1994, although the bulk of the coverage is from the 1970s. The strength of the collection is the documentation of the development of gerontological medicine at the University of Michigan, particularly the founding of the Turner Geriatric Clinic in 1977. There is very little in this collection, however, relating to Duff's prior activities or to the Rackham Arthritis Research Unit which he directed from 1953 until 1969 (for information on this unit researchers should consult the separate record groups, Rackham Arthritis Unit and the University of Michigan Department of Internal Medicine).

Collection

John C. Floyd Papers, 1960-1978

1.5 linear feet

Professor of internal medicine at the University of Michigan. Laboratory workbooks on diabetology and endocrinology from 1960 to 1978.

The collection consists primarily of laboratory workbooks of various experiments conducted between 1960 and 1978. The workbooks concern such subjects as the iodination of insulin, the immunization of guinea pigs, and the immuno assay of insulin.

A second set of workbooks concern the growth hormone. Unfortunately workbooks 4-8 are missing from this set. The third sequence of workbooks relate to insulin radioiodination.

Additionally, the collection includes experimental notes on glucagon radioiodination and gastrin iodination. The last workbook consists of quality control estimates for the HPP assay. There is also one folder of unidentified results from 1962. For a fuller understanding of the results of the assays, please consult the curriculum vitae for published articles on these topics.

Collection

William Dodd Robinson Papers, 1933-1989 (majority within 1933-1976)

2.5 linear feet

Professor of internal medicine at the University of Michigan; head of the Rackham Arthritis Research Unit (RARU) at the university. Papers relating to Robinson's career as doctor and professor of arthritis and rheumatology; includes material on work at the University of Michigan, Vanderbilt University, and the Rockefeller Foundation; correspondence, research projects, lecture materials, reports, meeting minutes, professional activities, awards and honors, papers, and visual materials; also correspondence and other miscellaneous materials relating to Louis Harry Newburgh.

William Dodd Robinson's papers have been arranged into four series: University of Michigan; Research Projects; Professional Activities; and General Materials.